bonus

Mini Episode: The Saga of the Cardiac Action Potential

  • Action potential
  • Sodium/Potassium ATPase pumps create more positively charged ions outside the cell than inside the cell, this creates a relative negative charge in the cell
  • Phase 4- Resting (~ -90 mv)
  • Phase 0- Sodium enters the cell (+10 mv) 
  • Phase 1- Potassium efflux from cell as now there is no negative charge holding it in (0 mv)
  •  Phase 2- Calcium channels open and allow calcium in, calcium triggers the ryandoine receptor and allows for calcium dependent calcium release from the sarcoplasmic reticulum occurs
  • Phase 3- Potassium continues to leave the cell  allowing return to -90 mv 

Support the show

Review the show where ever your listening

Get Messages from Toxo (Join the Newsletter!)

Join as a supporting member

  • Ad free episodes
  • Bonus content and early access
  • Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!

The Poisonus Fungus Amongus Children's Book!

Tox trinkets (Rep the show at home!)

Reach the show

  • Email: Toxtalk1@gmail.com

More Show Resources

Next Episode All Episodes Previous Episode

About the Podcast

Show artwork for The Poison Lab
The Poison Lab
Explore the world of poisoning with Clinical Toxicologist Ryan Feldman and Cohost Toxo, dive into the history, science, and life-saving care of poisoning. Survivor stories, expert insights, and deep dives—every poison has a story to tell!

Listen for free

About your host

Profile picture for Ryan Feldman

Ryan Feldman

Dr. Ryan Feldman PharmD, DABAT is the chief scientist at The Poison Lab. He works as a Clinical Toxicologist, Emergency Medicine Pharmacist, and Clinical Assistant Professor of Pharmacy and Emergency medicine.